one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: That is an impurity connected to bortezomib, a proteasome inhibitor Employed in the therapy of various myeloma. Its synthesis or study is essential for guaranteeing the purity and security from the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor during the synthesis of abiraterone acetate, a drug used in the procedure of prostate cancer by inhibiting androgen generation.
Imatinib Intermediate (CAS NO. 152460-ten-1): A vital compound inside the synthesis of imatinib, a drug that targets precise kinds of cancer, including Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats numerous cancers which include breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They're intermediates from the synthesis of gemcitabine, an anti-cancer drug. Their study is significant for optimizing the manufacturing system 17-diol 17-acetate and ensuring large purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is employed to deal with breast cancer, and these intermediates are involved in its generation.
Fulvestrant Intermediates: Fulvestrant is an estrogen receptor antagonist used in the cure of breast most cancers. Numerous intermediates help in the synthesis of this drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-sixteen-9): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug helpful in dealing with cancers for instance ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Employed in the remedy of 1-AMINO-3-ADAMANTANOL colorectal most cancers and small cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is associated with the synthesis of adamantane derivatives, that have a variety of purposes, such as antiviral Houses.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for type two diabetic issues that inhibits the enzyme DPP-four to manage blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-one): This compound is associated with the synthesis of varied gluconic acid derivatives, which can be Employed in food, pharmaceutical, and industrial programs.
Canagliflozin Intermediate two: A precursor in the synthesis of canagliflozin, a medication utilized to manage variety 2 diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).